What is GW 501516 (Cardarine)?

GW 501516 (or Cardarine), is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.

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As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it “the ultimate endurance enhancing supplement.”

Plus, Cardarine’s ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete’s cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.

Let’s take a closer look…

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How It Works

GW 501516 is is a PPARδ agonist and NOT a SARM, but does work in very similar ways. In this case, GW 501516 targets the androgen receptors that stimulate glucose uptake and skeletal muscle tissue. Currently, it is being suggested as a potential treatment for obesity by rapidly melting through through what’s called “fatty acid oxidation“.

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Also, Cardarine is said to increase HDL by an average of 79% (good cholesterol) and decrease LDL (bad cholesterol) in current Phase II trials.

These help increase your HDL levels from an enhanced expression of the cholesterol transporter ABCA1.

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The Benefits of GW 501516

The benefits of Cardarine seem to be endless, both in medical science and in the gym. Many studies have been done on GW 501516 showing numerous positive effects during trial, despite minimum side effects.

That is part of the reason why Cardarine has recently become so popular.

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Below are a list of the most powerful benefits that you could experience while taking a cycle of GW 501516 (compiled from much research and study)

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The Ultimate Endurance Supplement

GW 501516 is literally the best it gets when it comes to endurance, energy, stamina, and performance enhancement of any kind.

It is used by elite athletes for a reason, from cyclists to elite bodybuilders. In fact, WADA has even addded GW 501516 to their list of banned substances because of it’s competitive advantage.

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You can expect insane levels of intensity in the gym, shorter recovery times, and be able to bust through plateaus like never before.

Also, the energy you get from Cardarine is not experienced as jittery or anxious. It’s not a stimulant, and you won’t crash hours later.

In fact, many users even report feeling an overall sense of well being and calmness.

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Some of the other benefits include:

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• Rapidly melts fat and NON catabolic.

• Provides noticeable results on the first dose.

• The ability to run for as long as 8-12+ weeks.

• Is versatile and can be stacked with anything.

• Can be used while cutting OR bulking.

• No side effects, liver toxicity, or suppression have been reported.

• No need for a PCT

 

Cardarine: The Cure for Obesity?

THE PRIMARY ROLE is GW’s ability to rid the body of unwanted fatty tissue and it has become almost LEGENDARY. The chemical compounds in this particular PPAR agonist functions in differentiation of adipocytes.

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Much like growth hormone, GW 501516 generates proinflammatory markers in adipose tissue and decreasing the activity of genes involved in lipogenesis. This means that the body is able to block fatty acid chains from forming and being stored as fat.

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A study from Scientific Reports published in 2015 stated:

“GW501516 acts on PPAR beta cells that exclusively use body fat as energy in the same way the body would when going through “starvation mode”.

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Side Effects

Not to say that there are none, but in the last 20 years no side effects have been seen by anyone studying the drug.

GW501516 has not only been tested in healthy subjects, but also those with simulated “real life” habits (such as drinking alcohol, stimulant narcotics, and the use of tobacco products). It is uncertain if there are long term ramifications, but no research has been published stating otherwise.

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This is what makes Cardarine so incredibly popular and usable over long periods of time. In certain studies, there have even been signs showing the reversal of diabetes, obesity, Dyslipidemia and many other diseases.

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Liver Damage

In contrast to popular belief, GW501516 doesn’t promote damage of liver cells. The chemical has actually been known to promote healthy liver function and faster healing properties to the skin and muscle tissue. In essence, you will not heal rapidly like Wolverine from the X Men movies, but you will shorten the your recovery time from scratches, blisters, and injured muscles by a significant amount.

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Recommendations & Dosing Guidelines for Cardarine

• 10-20 mg per day is a sufficient dose. It is recommended to start at 10mg per day to take advantage of the host’s sensitivity to the new chemical. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be

• Lab mice should be given dosages 45 minutes- 1 hour before exercise.

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• GW501516 has been tested for a 2 year study and has found no decreases or stagnation in effects. Most individuals run cycles for 12-14 weeks at a time with a 4-6 week break. This is normally to coincide with a SARM cycle, but there is no evidence showing that GW 501516 needs to be off-cycled after such a short amount of time. GW 501516 was created for LONG TERM usage, so there is no reason why it shouldn’t be used that way.

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• Half life is between 16-24 hours and should be take at 10mg once a day or 10mg once every 10-12 hours if taken at a higher dose.

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• No PCT is needed, GW is recommended in combination with PCT if highly toxic anabolics have been used.

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• Highly recommended to use with a ketogenic diet.

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• Can be used in conjunction with anabolics and stimulants of any kind without adverse reactions.

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Final Takeaway

After a lot of research and personal use, there is nothing I can recommend more than Cardarine. It is the king of all fat burners and reigning champion of endurance supplements. GW 501516 has received many rave reviews from its users. One user even said “…GW is probably the closest thing in research to a perfect formula. Stamina and fat loss is unreal!…” There’s no doubt this is the Clenbuterol of PPARs.

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It’s true that most athletes and professional bodybuilders simply lack the endurance and cardio levels to get the results they want. With GW, you can actually add lean mass while reducing body fat…something you can’t do taking anything else. You’ll be able to lift longer and harder, and with an intensity never known to you before. This obviously is what it takes to get results and get them fast.