Selective Androgen Receptor Modulators (SARMS)
What are SARMs?
SARMS, or selective androgen receptor modulators, are a unique class of molecules that are being developed to treat diseases that are currently being treated with AAS (anabolic-androgenic steroids). Some SARMS have even gone to trial for TRT (testosterone replacement therapy).
When SARMS bind to the receptor they demonstrate anabolic and hypertrophic activity in both muscle and bone. This makes them ideal candidates for TRT, osteoporosis treatment and muscle wasting treatment.
For bodybuilders, SARMS provide the benefits of traditional AAS (anabolic-androgenic steroids) - more muscle, less fat, and better bone density - while producing significantly fewer unwanted side effects (estrogen related sides and water retention).
SARMS can have an anabolic to androgenic ratio as high as a 10:1. This is what allows them to build muscle with little to no side effects. They also typically display a high bioavailability, ensuring effective utilisation and absorption.
Benefits of SARMs over AAS
SARMS are nontoxic to the liver and have little effect on blood pressure. This eliminates the need for preloading and on-cycle support supplements. Subsequently, a SARM cycle will ultimately be less expensive than a traditional AAS/Ph (steroid/prohormone) cycle. The chances of estrogen-related sides and water retention are significantly lower, as well.